Guinea Bissau stunned the Super Eagles Naira 0-1 in a 2023 Africa Cup of Nations qualifier at the Moshood Abiola National Stadium in Abuja.
A 29th-minute goal was all the visitors needed to shock the 2013 AFCON winners on home soil and hand them a famous victory.
With two previous wins from two matches, the Eagles were looking to stretch their lead in group A.
The second leg of the match between both teams is scheduled for March 27 at the Estádio 24 in Bissau.